The Incidence and Prevalence of Crohn’s Disease in Global Scale

نویسندگان

  • Payam Behzadi
  • Elham Behzadi
  • Reza Ranjbar
چکیده

The clear etiopathogenesis of CD is not recognized yet; but, there is a triangle of the main predisposing factors such as genetic, immunologic and peripheral parameters which triggers the disease. In other word, genetic malfunctions regarding to immune system in parallel with environmental factors like human gut microbiota, foods, smoke, chemical contamination induce the occurrence of CD in predisposed people. The environmental risk factors increase the appearance of CD in immune dysregulated individuals up to 40 times [1,2,4,5,6].

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تاریخ انتشار 2015